Hydroxypropyl Gamma Cyclodextrin
Hydroxypropyl Gamma Cyclodextrin
Products Description
Hydroxypropyl- gamma-cyclodextrin belongs to the class of cyclodextrin derivatives, which exhibit a greater extent of solubility in water compared to their parent compounds. It is widely used in parenteral formulations and solid dosage forms to aid in the improvement of their stability, dissolution, bioavailability, etc.
Characteristics
Hydroxypropyl gamma cyclodextrin dissolves large molecules, such as cholesterol, for cell culture. It is similar to betacyclodextrin, but can dissolve larger molecules.
Application
The water solubility of hydroxypropyl – γ – cyclodextrin was further increased to 80g / 100ml (25 ℃). At the same time, the hydroxypropyl – γ – cyclodextrin was no longer a single pure product, but a mixture of multiple substitutions. It was not easy to form inclusion complex crystal precipitation when it was combined with guest molecules. In general, hydroxypropyl – γ – cyclodextrin had higher water solubility and stronger anti-oxidation ability The ability of crystallization. The solubility of γ – cyclodextrin in water is 23.2g/100ml (25 ℃), and its application is limited in some cases.
Basic Analysis
| ITEMS | CRITERIA |
| Appearance | White or almost white powder;Odorless,slightly sweet;Freely soluble in water,soluble in ethanol,almost insoluble in acetone. |
| Water solution pH | pH5.0~8.5 |
| Light-absorbing impurities | Between 230 and 350 nm,the absorbance is NMT 0.5; and between 350 and 660 nm, the absorbance is NMT 0.5. |
| Water | ≤10.0% |
| Gamma Cyclodextrin | ≤1.5% |
| Residue on ignition | ≤0.2% |
| Heavy Metal | ≤10ppm |
| Propylene glycol | ≤0.5% |
| Assay | ≥95% |
| Hydroxypropoxyl content | 17.5%~29.1% |
| The total aerobic microbial count | ≤1000cfu/g |
| The total combined moulds and yeasts count | ≤100cfu/g |
| Escherichia coli | Absence |
| Bacterial Endotoxins Test | According to preparation needs |
Gmo Statement
We hereby declare that, to the best of our knowledge, this product was not produced from or with GMO plant material.
Ingredient Statement
Statement Option #1: Pure Single Ingredient
This 100% single ingredient does not contain or use any additives, preservatives, carriers and/or processing aids in its manufacturing process.
Statement Option #2: Multiple Ingredients
Must include all/any additional sub ingredients contained in and/or used in its manufacturing process.
Gluten Free Statement
We hereby declare that, to the best of our knowledge, this product is gluten-free and was not manufactured with any ingredients containing gluten.
(Bse)/ (Tse) Statement
We hereby confirm that, to the best of our knowledge, this product is free of BSE/TSE.
Cruelty-Free Statement
We hereby declare that, to the best of our knowledge, this product has not been tested on animals.
Kosher Statement
We hereby confirm that this product has been certified to Kosher standards.
Vegan Statement
We hereby confirm that this product has been certified to Vegan standards.
Food Allergen Information
| ALLERGENS | PRESENCE | ABSENCE | PROCESS COMMENT |
| Milk or milk derivatives | No | Yes | No |
| Egg or egg derivatives | No | Yes | No |
| Fish or fish derivatives | No | Yes | No |
| Shellfish, crustaceans, mollusks & their derivatives | No | Yes | No |
| Peanuts or peanut derivatives | No | Yes | No |
| Tree nuts or their derivatives | No | Yes | No |
| Soy or soy derivatives | No | Yes | No |
| Wheat or wheat derivatives | No | Yes | No |
Trans Fat
This product does not contain any trans fats.